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CMCC 846

Novel AIDS Vaccine

Inventors: Anna Aldovini, Shainn-Wei Wang

Invention Types: Other

Research Areas: Immunology, Infectious Disease

Keywords: Vaccine

For More Information Contact:  Meyer, Abbie

 

Invention Description:

DNA-based vaccine for HIV, with a design that is applicable to other virus vaccines. The DNA is a vector encoding a non-infectious, synthetic HIV virus containing extensively mutated proteins. Some mutations enhance the synthetic virus's ability to elicit immunity against HIV; other mutations deactivate important viral proteins. The DNA-based vaccine is modifiable in composition and expression, and flexible with regard to route of administration. Described is a pilot evaluation of the invention in primates. A report with methods for effective induction of mucosal SIV immune responses is included.

Applications:

Vaccine

Research Tool

Competitive Advantages:

The DNA-based vaccine is modifiable in composition and expression, and flexible with regard to route of administration. A pilot evaluation of the invention in primates, and a report with methods for effective induction of mucosal SIV immune responses are included.

Business Opportunity:

Exclusive License

Key Publications: US patent number 7,122,180|
issued on October 17, 2006

IPStatus: Patented