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CMCC 2615

Device and methods for analyzing rodent behavior using light technology

Inventors: Clifford Woolf, David Roberson, Alex Wiltschko, Sandeep Datta

Invention Types: Research Tool

Research Areas: Neurology/Neuroscience, Pain

Keywords: Instrumentation, Method of Use

For More Information Contact:  Caron, Connie

 

Invention Description:

Dr. Woolf and his team, in collaboration with Dr. Datta at Harvard, have developed a device and research methodology for the acquisition and analysis of animal behavior through the imaging of inferior surfaces, such as the plantar surface of paws and inferior body parts of freely behaving laboratory rodents. The device utilizes a horizontal transparent contact sensor positioned above a video camera. During experiments, the subject animal is placed in an open chamber directly on top of the sensor, while being video recorded from below. In this implementation, the mouse can be observed for voluntary behaviors, rather than evoking a forced behavior in response to a stimulus or from within an artificially constrained environment. This device allows for nocturnal observation of mice to more accurately analyze behavioral patterns. This instrument allows for a more varied and richer array of inputs within an environment that is less constrictive, and therefore more accurate, than existing implementations.

Applications:

The rodent behavior detection and analysis technology may be used to determine whether a certain medication, stimulus or environment has a consequence on an animal's behavior.

Competitive Advantages:

• Usage of both visible and non-visible infrared allows for nocturnal observation.

• Technology allows for unimpeded movement, encouraging voluntary spontaneous behavior.

• Technology captures behavioral data for a variety of innate behaviors beyond animal gait analysis.

Business Opportunity:

Exclusive or non-exclusive license

Related Publications: https://vector.childrenshospital.org/2018/01/six-technologies-boston-childrens-hospital-backed-2017/

IPStatus: Pat. Pend.