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CMCC 2462

Detection of epilepsy with analysis of electromagnetic signals (EEG)

Inventors: William Bosl, Tobias Loddenkemper

Invention Types: Information Technology/Software, Medical Device

Research Areas: Neurology/Neuroscience

Keywords: Software

For More Information Contact:  Yen, Alan

 

Invention Description:

Epilepsy, one of the most prevalent chronic neurological diseases, affects approximately 0.6-1% of the general population, representing an economic burden of 0.1-1% of the total budget of health care systems in some parts of the world, and a significant proportion of these costs can be attributed to the way in which epilepsy is diagnosed. Epilepsy is characterized by the predisposition to develop spontaneous unprovoked seizures (epileptogenicity). Conventional methods for diagnosing epilepsy involve several clinical visits and workup studies, making it time-consuming and very expensive. More importantly, the diagnosis of several seizures only provides an approximation to the diagnosis of epilepsy.|

Drs. Bosl and Loddenkemper have recognized that electric or electromagnetic signals from patients with a propensity of having seizures may provide reliable biomarkers for diagnosing epilepsy. By matching clinical events that are suggestive of seizures with the concomitant electroencephalogram (EEG) recording, the investigators have identified measurable nonlinear features in the EEG signals that may be used as biomarkers to diagnose epilepsy without the need to identify the occurrence of repeated seizures.|

This technology includes algorithms, computer-readable media, and computer systems for analysis of electromagnetic data for the detection of reliable biomarkers for epilepsy.

Applications:

EEG algorithms and software for the diagnosis of epilepsy

Competitive Advantages:

• A Conventional methods for diagnosing epilepsy involve clinical visits and workup studies and only provides an approximation to the diagnosis of epilepsy.

• A Because of their unpredictable nature, seizures are often difficult to observe while a patient is in the clinic, and this often leads to a delay in the diagnosis of epilepsy, which in turn delays treatment for the patient. |
• A This technology allows for diagnosis of epilepsy in high-risk patients before the patient has had multiple seizures.

Business Opportunity:

Collaboration for development or exclusive license.

IPStatus: Pat. Pend.