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CMCC 2220

ICISS: Clinical knowledge management system for children with developmental disorders.

Inventors: Eric Fleegler, GLenn Marmon, Aaron Pikcilingis, Eugenia Chan

Invention Types: Information Technology/Software

Research Areas: Psychiatric Disease

Keywords: Software

For More Information Contact:  Yen, Alan

 

Invention Description:

When monitoring how treatment is progressing for a child with developmental disorders, a clinician may find it difficult to obtain critical information in a timely manner. The patient's caregivers are positioned to provide valuable information to guide future clinical treatment decisions. Questions such as -- how well is therapy working; are there any drug-related side effects; what has worked for similar patients; and what is causing symptom flare ups -- could be answered by parents and teachers. |

Drs. Eric Fleegler and Eugenia Chan developed a software system to collect these types of data through user-friendly online software system. The software allows for medication confirmation and side effects reporting, disease symptom surveys and quality of life measures. The data collected are scored automatically and displayed to clinicians in graphical, tabular and narrative formats through an interactive interface. The system is currently in use at Children's Hospital Boston Division of Developmental Medicine and since 2010 over 1500 patients have enrolled in the system. The system has helped reduce average doctor visit time, allowed clinicians to tailor treatment decisions to patient-reported data and enabled better tracking of patient condition over time. The response rate to obtain information from patients, parents and teachers has risen from between 10-30% to now over 50%. The researchers are striving to increase the response rate by continually improving user experience, including introducing a mobile interface in the near future.

Applications:

ICISS software can be used across patients and clinics to examine trends, and develop treatment goals and best practices. These include efficiency and cost trends, effectiveness trends, and treatment targets for providers and clinics. Children's Hospital Boston plans to expand ICISS to help manage autism, epilepsy, depression and asthma, among other conditions.

Competitive Advantages:

• ICISS represents a clinically relevant use of an electronic patient portal: patient families are motivated to comply with data entry; clinicians are motivated to review the information.

• Collected information offers an opportunity for aggregate data views to help develop group and individual baselines and provide decision support.

• Longitudinal data may be used to create decision support algorithms. |
• EMR compatible: natural language processing algorithms populate prose notes that can be copied and pasted into EMR.

• ICISS is a flexible platform that can be expanded to multiple indications including autism, depression and other mental health applications as well as other chronic conditions such as asthma and epilepsy.

• ADHD niche market entry will provide strategic advantage: There is an unmet need in the ADHD market. Lack of understanding of therapeutic responsiveness combined with an expanding patient population (children and adults), will help ICISS to enjoy adoption among primary care physicians and specialists.

• Physician designed interface ensures that the system will meet clinical needs.

Business Opportunity:

We are seeking collaboration and commercialization partners to make ICISS more widely available.

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