Return to Main Site 617-919-3019
401 Park Drive, 7th Floor East, Boston, MA 02215

TIDO Technology Search



Invention Type

Diagnostic/Prognostic
Information Technology/Software
Medical Device
Other
Research Tool
Therapeutics

Research Area

Allergy/Respiratory/Pulmonary Disease
Anesthesia
Audiology
Cardiovascular/Cardiology
Degenerative Disease
Dermatology
Endocrinology
Gastrointestinal/Nutrition
Genetic Disease
Health Care Management
Immunology
Infectious Disease
Inflammation
Internal Medicine
Metabolic Disease
Musculoskeletal
Neonatology/Pediatric
Neurology/Neuroscience
Oncology/Hematology
Ophthalmology
Orthopedics
Otolaryngology/Audiology
Pain
Pathology
Personalized Medicine
Psychiatric Disease
Radiology
Regenerative Medicine
Reproduction/Ob-Gyn
Stem Cell
Surgery/Wound Healing
Urology
CMCC 2154

Devices and methods of papillary muscle approximation for tricuspid valve repair and ventricular remodeling

Inventors: Pedro del Nido, Nikolay Vasilyev

Invention Types: Medical Device

Research Areas: Cardiovascular/Cardiology

Keywords: Surgery

For More Information Contact:  Miracco, Amy

 

Invention Description:

Tricuspid regurgitation (TR) adversely affects cardiac mortality. In adults, common mechanisms of “functional” TR are tricuspid annular dilation and right ventricular enlargement. Current methods of treatment include tricuspid annuloplasty, which has been shown to have only limited long-term effectiveness. Of particular note is this method’s ineffectiveness in the treatment of children for whom the procedure can inhibit otherwise healthy growth of the heart muscles. Dr. Del Nido and his team have developed a device that addresses this issue. Their approach is innovative both in the manner of construction and deployment of the device to the affected area. The device can non-invasively approximate cardiac tissue in a strategic manner to combat the effects of annulus and ventricular dilation.

Applications:

The device can be used across patient types as an in vivo mitigation factor of TR.

Competitive Advantages:

• Corrects the displaced papillary muscle head during open heart procedure and in a beating heart without cardiopulmonary bypass.

• Addresses papillary muscle displacement, ventricular dilation, and annular dilation.

• Provides a longer-lasting, less error-prone mechanism for repairing tricuspid valves, particularly in children.

Business Opportunity:

Exclusive License, Collaboration

Key Publications: Yamauchi et al. Right Ventricular papillary muscle approximation as a novel technique fo valve repair for functional tricuspid regurgitation in an ex vivo porcine model. J. Cardiovas. Surg. 2012;144: 235-42.

IPStatus: Pat. Pend.