Devices and methods of papillary muscle approximation for tricuspid valve repair and ventricular remodeling
Inventors: Pedro del Nido, Nikolay Vasilyev
Invention Types: Medical Device
Research Areas: Cardiovascular/Cardiology
Keywords: SurgeryFor More Information Contact: Miracco, Amy
Tricuspid regurgitation (TR) adversely affects cardiac mortality. In adults, common mechanisms of “functional” TR are tricuspid annular dilation and right ventricular enlargement. Current methods of treatment include tricuspid annuloplasty, which has been shown to have only limited long-term effectiveness. Of particular note is this method’s ineffectiveness in the treatment of children for whom the procedure can inhibit otherwise healthy growth of the heart muscles. Dr. Del Nido and his team have developed a device that addresses this issue. Their approach is innovative both in the manner of construction and deployment of the device to the affected area. The device can non-invasively approximate cardiac tissue in a strategic manner to combat the effects of annulus and ventricular dilation.
The device can be used across patient types as an in vivo mitigation factor of TR.
• Corrects the displaced papillary muscle head during open heart procedure and in a beating heart without cardiopulmonary bypass.
• Addresses papillary muscle displacement, ventricular dilation, and annular dilation.
• Provides a longer-lasting, less error-prone mechanism for repairing tricuspid valves, particularly in children.
Exclusive License, Collaboration
Key Publications: Yamauchi H, et al. Right ventricular papillary muscle approximation as a novel technique of valve repair for functional tricuspid regurgitation in an ex vivo porcine model. J Thorac Cardiovasc Surg. 2012 Jul;144(1)235-42.
IPStatus: Pat. Pend.