Enabling Devices for Beating Heart Intracardiac Surgery - 1 (Valve Repair Clip)
Inventors: Pedro del Nido, Nikolay Vasilyev, Franz Freudenthal
Invention Types: Medical Device
Research Areas: Cardiovascular/Cardiology
Keywords: For More Information Contact: Miracco, Amy
To enable the adoption of beating heart surgery for any type of heart procedure, including intracardiac interventions, unique instruments and techniques need to be developed. Children's Hospital Boston introduces a set of novel technologies that are enabling for beating heart surgery. One set of instruments is a valve repair clip and delivery device for correcting mitral valve regurgitation due to mitral valve prolapse. The clip is loaded in its customized delivery device and is deployed inside the beating heart through a specially designed surgical port. Feasibility studies have demonstrated successful elimination of the prolapse on isolated porcine hearts. Flow dynamic studies have demonstrated the correction of the mitral valve regurgitation to be persistent.
The valve repair clip and delivery device were specifically designed to correct mitral valve prolapse. The introduction of beating heart surgery would complement the recent interest in and adoption of minimally invasive procedures in cardiac surgery. Minimally invasive (i.e., minimal incision) procedures offer improvements in patient outcome and recovery time; beating heart surgery eliminates the risks associated with cardiopulmonary bypass. The combination of these two approaches would enhance the cardiac surgeon's ability to correct life threatening conditions with less discomfort and risk to the patient. In addition to the cardiac application, the valve repair clip could conceivably provide a user friendly means of closing wounds.
The patient benefits of beating heart intracardiac surgery are clear: decreased risk of ischemic damage to the heart muscle and of causing stroke, less pain and trauma, reduced morbidity and mortality and shorter hospital stay and subsequent recovery time. The recent widespread adoption of real-time 3D echocardiography in the operating room facilitates the use of these instruments for mitral valve repair by informing instrument and device navigation and deployment. The specially designed surgical port to be used for the safe introduction of the clip into the beating heart has been prototyped and tested. These instruments require no additional infrastructure beyond what is in the operating room already and are cost-comparable to currently used devices.
Key Publications: Feins EN, Yamauchi H, Marx GR, et al. Repair of posterior mitral valve prolapse with a novel leaflet plication clip in an animal model. J Thorac Cardiovasc Surg. 2014 Feb; 147(2): 783-791.